3041973-64-9
3041973-64-9
Chemical Structure
TBK1-IN-1
- CAS No.: 3041973-64-9
- Formula:C27H35N7O2
- Molecular Weight:489.61
IUPAC Name: 4-chloro-2-(pyridin-4-yl)pyrido[3,4-d]pyrimidine
InChIKey: QVADRMQCYNOPPE-UHFFFAOYSA-N
SMILES: CC(N1CCN(CC1)CC2=CC=CC(NC3=NC=C4C=CN(C4=N3)CCCNC(C5CCC5)=O)=C2)=O
Biological Activity: TBK1-IN-1 is a potent and selective TANK binding kinase 1 (TBK1) inhibitor with an IC50 value of 22.4 nM. TBK1-IN-1 inhibits TBK1 downstream target genes cxcl10 and ifnβ expression. TBK1-IN-1 has anticancer activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TBK1-IN-1 | 99.63% | TBK1-IN-1 is a potent and selective TANK binding kinase 1 (TBK1) inhibitor with an IC50 value of 22.4 nM. TBK1-IN-1 inhibits TBK1 downstream target genes cxcl10 and ifnβ expression. TBK1-IN-1 has anticancer activity. | ||||||||||||||||||||
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