3043725-09-0
3043725-09-0
Chemical Structure
TI-61987
- CAS No.: 3043725-09-0
- Formula:C18H14N4O3
- Molecular Weight:334.33
InChIKey: GRLNSXBBJQRXHS-UHFFFAOYSA-N
SMILES: O=C(NC1=C2C=CNC2=CC=C1)CN3NC(C4=CC=CC=C4C3=O)=O
Biological Activity: TI-61987 is a TNKS1/2 inhibitor. TI-61987 inhibits TNKS1 and TNKS2 with IC50 values of 7.3 nM and 12 nM, respectively, stabilizes AXIN, and reduces active β-catenin. TI-61987 exhibits weak inhibitory activity against PARP1 and PARP2 enzymatic activity. TI-61987 can be used for research on colorectal cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TI-61987 | TI-61987 is a TNKS1/2 inhibitor. TI-61987 inhibits TNKS1 and TNKS2 with IC50 values of 7.3 nM and 12 nM, respectively, stabilizes AXIN, and reduces active β-catenin. TI-61987 exhibits weak inhibitory activity against PARP1 and PARP2 enzymatic activity. TI-61987 can be used for research on colorectal cancer. | |||||||||||||||||||||
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