3046195-01-8
3046195-01-8
Chemical Structure
PTOTAC HSD17B13 degrader 1
- CAS No.: 3046195-01-8
- Formula:C45H45ClF3N7O5
- Molecular Weight:856.33
InChIKey: PUPPJGPTCPHCGA-WTCBJYTRSA-N
SMILES: O=C1N(C2C(NC(CC2)=O)=O)C3=CC=C(CCCN4CC5=CC(C6=CC7=NN([C@@H]8CC[C@H](CC8)CNC(C9=C(C(F)=C(C(F)=C9)O)F)=O)C=C7C=C6)=CC=C5C4)C=C3N1C.Cl
Biological Activity: PTOTAC HSD17B13 degrader 1 is a HSD17B13 PROTAC degrader with a DC50 of 0.11 nM. HSD17B13 is a liver lipid droplet-associated medium-chain dehydrogenase/retinol dehydrogenase. PTOTAC HSD17B13 degrader 1 can be used in liver cancer research[1].
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PTOTAC HSD17B13 degrader 1 | PTOTAC HSD17B13 degrader 1 is a HSD17B13 PROTAC degrader with a DC50 of 0.11 nM. HSD17B13 is a liver lipid droplet-associated medium-chain dehydrogenase/retinol dehydrogenase. PTOTAC HSD17B13 degrader 1 can be used in liver cancer research. | |||||||||||||||||||||
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