3046390-69-3
3046390-69-3
Chemical Structure
FXIa-IN-16
- CAS No.: 3046390-69-3
- Formula:C24H18ClFN8O2
- Molecular Weight:504.90
InChIKey: SLYRYQGKFIGQJP-UHFFFAOYSA-N
SMILES: O=C1N(CC2=NC=CC(C3=C(F)N=C(N)C=C3)=C2)C=C(OC)C(C4=CC(Cl)=CC=C4N5C=NN=N5)=C1
Biological Activity: FXIa-IN-16 is an orally active selective FXIa inhibitor with an IC50 of 0.19 nM. FXIa-IN-16 exerts highly selective competitive inhibition on endogenous FXIa, blocks the thrombin amplification loop to inhibit thrombosis, while preserving exogenous physiological hemostatic function. FXIa-IN-16 can be used in thrombosis-related research[1].
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FXIa-IN-16 | FXIa-IN-16 is an orally active selective FXIa inhibitor with an IC50 of 0.19 nM. FXIa-IN-16 exerts highly selective competitive inhibition on endogenous FXIa, blocks the thrombin amplification loop to inhibit thrombosis, while preserving exogenous physiological hemostatic function. FXIa-IN-16 can be used in thrombosis-related research. | |||||||||||||||||||||
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