3048497-38-4
3048497-38-4
Chemical Structure
OZD-MET 01
- CAS No.: 3048497-38-4
- Formula:C45H50Cl2FN7O8
- Molecular Weight:906.83
InChIKey: OFMNSOFELBXNIT-HHHXNRCGSA-N
SMILES: C[C@@H](OC1=CC(C2=CN(N=C2)C3CCN(C(OCCOCCNC(C4=CC(CN(C(C5=CC(C(C)C)=C(O)C=C5O)=O)C)=CC=C4)=O)=O)CC3)=CN=C1N)C6=C(Cl)C(F)=CC=C6Cl
Biological Activity: OZD-MET 01 is a chaperone-based PROTAC-class MET protein degrader. OZD-MET 01 induces MET protein degradation in lung cancer cells in a time- and dose-dependent manner and inhibits cancer cell proliferation. OZD-MET 01 can be used in studies related to non-small cell lung cancer[1].
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OZD-MET 01 | OZD-MET 01 is a chaperone-based PROTAC-class MET protein degrader. OZD-MET 01 induces MET protein degradation in lung cancer cells in a time- and dose-dependent manner and inhibits cancer cell proliferation. OZD-MET 01 can be used in studies related to non-small cell lung cancer. | |||||||||||||||||||||
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