3049087-34-2
3049087-34-2
Chemical Structure
NC-R17
- CAS No.: 3049087-34-2
- Formula:C53H67N7O7
- Molecular Weight:914.14
InChIKey: RFACIWXTBIAVON-VSDRZZBPSA-N
SMILES: O=C(OC)[C@@H]1N(C(CC)=O)[C@@H](C2=CC=C(C(N3CCN(CCCCCCCCCCCCCNC4=C(CN(C5C(NC(CC5)=O)=O)C6=O)C6=CC=C4)CC3)=O)C=C2)C7=C(C(C=CC=C8)=C8N7)C1
Biological Activity: NC-R17 is a PROTAC degrader that targets glutathione peroxidase 4 (GPX4) for degradation by recruiting cereblon. With RSL3 as its parent core, NC-R17 binds non-covalently to GPX4. NC-R17 exhibits moderate GPX4 degradation activity in tumor cells and can be used in studies related to ferroptosis (ferroptosis) and tumors[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
NC-R17 | NC-R17 is a PROTAC degrader that targets glutathione peroxidase 4 (GPX4) for degradation by recruiting cereblon. With RSL3 as its parent core, NC-R17 binds non-covalently to GPX4. NC-R17 exhibits moderate GPX4 degradation activity in tumor cells and can be used in studies related to ferroptosis (ferroptosis) and tumors. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
