3049215-64-4
3049215-64-4
Chemical Structure
BLK degrader 1
- CAS No.: 3049215-64-4
- Formula:C32H25F3N6O2
- Molecular Weight:582.58
InChIKey: MGJRUWHJBSOWPN-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1C(NC2=CN=C(N=C2)NC3=CC=CC(N)=C3)=O)NC(C4=CC=C(C=C4)C5=CC(C(F)(F)F)=CC=C5)=O
Biological Activity: BLK degrader 1 is a selective B lymphoid tyrosine kinase (BLK) degrader with a BLK DC50 of 49 nM in cells. BLK degrader 1 induces ubiquitin-proteasome-dependent BLK degradation through binding. BLK degrader 1 exhibits anticancer activity in multiple B lymphocyte cell lines and downregulates CDK2 protein levels. BLK degrader 1 can be used in research related to B cell lymphoma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BLK degrader 1 | 98.94% | BLK degrader 1 is a selective B lymphoid tyrosine kinase (BLK) degrader with a BLK DC50 of 49 nM in cells. BLK degrader 1 induces ubiquitin-proteasome-dependent BLK degradation through binding. BLK degrader 1 exhibits anticancer activity in multiple B lymphocyte cell lines and downregulates CDK2 protein levels. BLK degrader 1 can be used in research related to B cell lymphoma. | ||||||||||||||||||||
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