3052115-51-9
3052115-51-9
Chemical Structure
SIRT-IN-4
- CAS No.: 3052115-51-9
- Formula:C29H28ClFN4O2
- Molecular Weight:519.01
InChIKey: USLQGCUXEGLWGH-UHFFFAOYSA-N
SMILES: FC1=CC=CC(CN2CCCC(C2)CC3=NC(C4=CC=C(C=C4)NC(C5=CC=C(C=C5)Cl)=O)=NO3)=C1C
Biological Activity: SIRT-IN-4 is an inhibitor of the NAD+-dependent lysine deacetylase Sirtuin2 (Sirt2) (IC50=0.35 μM). SIRT-IN-4 is a potent Sirt2 deacetylase inhibitor that reduces cell survival and inhibits the migration of prostate cancer cells. SIRT-IN-4 can be used to study Sirt2 in cell cycle regulation, gene expression regulation, etc[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SIRT-IN-4 | SIRT-IN-4 is an inhibitor of the NAD+-dependent lysine deacetylase Sirtuin2 (Sirt2) (IC50=0.35 μM). SIRT-IN-4 is a potent Sirt2 deacetylase inhibitor that reduces cell survival and inhibits the migration of prostate cancer cells. SIRT-IN-4 can be used to study Sirt2 in cell cycle regulation, gene expression regulation, etc. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
