3052306-60-9
3052306-60-9
Chemical Structure
PI3K-IN-48
- CAS No.: 3052306-60-9
- Formula:C25H21FN2O4
- Molecular Weight:432.44
InChIKey: HADZLNXABXZMOJ-UHFFFAOYSA-N
SMILES: COC1=CC(OC)=C(C=C1C2=NC3=CC(OC)=C(C=C3N2)C#CC4=C(C=CC=C4)F)OC
Biological Activity: PI3K-IN-48 is a PI3K inhibitor with IC50 value of 1.55 ± 0.18 μM for A549 cells. PI3K-IN-48 can induce G0/G1 phase arrest, cell apoptosis, and down-regulate expression of p-PI3K and p-Akt. PI3K-IN-48 can be used for human lung cancers diseases research[1].
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PI3K-IN-48 | PI3K-IN-48 is a PI3K inhibitor with IC50 value of 1.55 ± 0.18 μM for A549 cells. PI3K-IN-48 can induce G0/G1 phase arrest, cell apoptosis, and down-regulate expression of p-PI3K and p-Akt. PI3K-IN-48 can be used for human lung cancers diseases research. | |||||||||||||||||||||
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