3052553-77-9
3052553-77-9
Chemical Structure
DUB-IN-8
- CAS No.: 3052553-77-9
- Formula:C24H25N5O2
- Molecular Weight:415.49
InChIKey: PRBPZYYSWGOXON-GXGIDHNPSA-N
SMILES: O=C(NCC1=CC=C(C(NC2[C@@H]3C[C@@H]4C[C@H]2C[C@@H](C4)C3)=O)C=C1)C5=CN=C(C#N)N=C5
Biological Activity: DUB-IN-8 (Compound 8q) is an inhibitor for Chlamydia deubiquitinase 1 (DUB1), with IC50 of 7.7 μM. DUB-IN-8 exhibits antimicrobial activity, inhibits the chlamydial inclusions with an IIC50 (the concentration to induce 50% inclusion inhibition) of 8.5 μg/mL[1].
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DUB-IN-8 | DUB-IN-8 (Compound 8q) is an inhibitor for Chlamydia deubiquitinase 1 (DUB1), with IC50 of 7.7 μM. DUB-IN-8 exhibits antimicrobial activity, inhibits the chlamydial inclusions with an IIC50 (the concentration to induce 50% inclusion inhibition) of 8.5 μg/mL. | |||||||||||||||||||||
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