3052688-17-9
3052688-17-9
Chemical Structure
HDAC-IN-64
- CAS No.: 3052688-17-9
- Formula:C15H8ClF4N7O
- Molecular Weight:413.72
InChIKey: MUCCBEWLLGMTNZ-UHFFFAOYSA-N
SMILES: NC1=NC(Cl)=C2N=CN(CC3=CC=C(C4=NOC(C(F)(F)F)=N4)C=C3F)C2=N1
Biological Activity: HDAC-IN-64 (Compound 13) is a HDAC inhibitor. HDAC-IN-64 inhibits HDAC4/5/6/7/9 with IC50s of 24, 45, 85, 31, 37 nM. HDAC-IN-64 has anti-proliferative activity and anti-migration properties on prostate cancer (PCA) cells. HDAC-IN-64 inhibits LNCaP and RWPE-1 cell growth with GI50 of 0.32 and 1.1 μM respectively[1].
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HDAC-IN-64 | HDAC-IN-64 (Compound 13) is a HDAC inhibitor. HDAC-IN-64 inhibits HDAC4/5/6/7/9 with IC50s of 24, 45, 85, 31, 37 nM. HDAC-IN-64 has anti-proliferative activity and anti-migration properties on prostate cancer (PCA) cells. HDAC-IN-64 inhibits LNCaP and RWPE-1 cell growth with GI50 of 0.32 and 1.1 μM respectively. | |||||||||||||||||||||
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