3053755-09-9
3053755-09-9
Chemical Structure
LMP7/LMP2-IN-1
- CAS No.: 3053755-09-9
- Formula:C16H27BN4O3
- Molecular Weight:334.22
InChIKey: SSGADSLNPZAYBK-HNNXBMFYSA-N
SMILES: OB(O)[C@@H](NC(C1=CN(C2CCCCC2)N=N1)=O)C3CCCCC3
Biological Activity: LMP7/LMP2-IN-1 (Compound 19) is the orally active inhibitor for immunoproteasome subunits LMP7 and LMP2 with IC50 of 257 and 10 nM. LMP7/LMP2-IN-1 reduces the generation of antibody, downregulates the cells in spleen germinal center B and in plasma in NP-OVA-immunized mice, and can be used in research about autoimmune diseases[1].
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LMP7/LMP2-IN-1 | LMP7/LMP2-IN-1 (Compound 19) is the orally active inhibitor for immunoproteasome subunits LMP7 and LMP2 with IC50 of 257 and 10 nM. LMP7/LMP2-IN-1 reduces the generation of antibody, downregulates the cells in spleen germinal center B and in plasma in NP-OVA-immunized mice, and can be used in research about autoimmune diseases. | |||||||||||||||||||||
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