3055854-78-6
3055854-78-6
Chemical Structure
CALR ligand 1
- CAS No.: 3055854-78-6
- Formula:C17H17ClN4O3S
- Molecular Weight:392.86
InChIKey: SOXIEWZLNREDAS-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(C2=CN=C3C(C(NC(CCl)=O)=NN3)=C2)C=C1)(C(C)C)=O
Biological Activity: CALR ligand 1 (Compound 2a) is a calreticulin (CALR) ligand. CALR ligand 1 shows antitumor activity against triple-negative breast cancer (TNBC) cells (IC50=0.1 μM). CALR ligand 1 induces intracellular calcium overloading and triggers apoptosis in TNBC cells. CALR ligand 1 is promising for research of TNBC [1].
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CALR ligand 1 | CALR ligand 1 (Compound 2a) is a calreticulin (CALR) ligand. CALR ligand 1 shows antitumor activity against triple-negative breast cancer (TNBC) cells (IC50=0.1 μM). CALR ligand 1 induces intracellular calcium overloading and triggers apoptosis in TNBC cells. CALR ligand 1 is promising for research of TNBC . | |||||||||||||||||||||
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