3056015-44-9
3056015-44-9
Chemical Structure
TDI-11904
- CAS No.: 3056015-44-9
- Formula:C23H24Cl2N4O3S
- Molecular Weight:507.43
InChIKey: JYBLFGNXDBGXEE-UHFFFAOYSA-N
SMILES: O=C1NC(C)=CC(SC)=C1CN2C(C3=C(C(C4=C(C)ON=C4C)=CC(Cl)=C3N(CC2)C)Cl)=O
Biological Activity: TDI-11904 is a peripherally active EZH2 inhibitor with an EZH2 IC50 of 0.9 nM. TDI-11904 inhibits EZH2 methyltransferase activity, reduces the trimethylation level of H3K27me3, and decreases intracellular H3K27me3 content. TDI-11904 inhibits the proliferation of lymphoma cells. TDI-11904 can be used for the research of lymphoma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
TDI-11904 | TDI-11904 is a peripherally active EZH2 inhibitor with an EZH2 IC50 of 0.9 nM. TDI-11904 inhibits EZH2 methyltransferase activity, reduces the trimethylation level of H3K27me3, and decreases intracellular H3K27me3 content. TDI-11904 inhibits the proliferation of lymphoma cells. TDI-11904 can be used for the research of lymphoma. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
