3056281-16-1
3056281-16-1
Chemical Structure
PD-1/PD-L1-IN-68
- CAS No.: 3056281-16-1
- Formula:C29H32N2O3
- Molecular Weight:456.58
InChIKey: FXCOARBIOAEGLF-UHFFFAOYSA-N
SMILES: COC1=C(CC(N2CCC(O)C2)=O)C=C(CCNC3CC4=CC=C(C5=CC=CC=C5)C=C4)C3=C1
Biological Activity: PD-1/PD-L1-IN-68 is a PD-L1 inhibitor based on a tetrahydroisoquinoline scaffold, with a KD of 21.31 μM for binding to hPD-L1, and it blocks the PD-1/PD-L1 interaction. PD-1/PD-L1-IN-68 restores T cell immune function, thereby promoting the death of PD-L1+ cancer cells. PD-1/PD-L1-IN-68 can be used in studies related to liver cancer[1].
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PD-1/PD-L1-IN-68 | PD-1/PD-L1-IN-68 is a PD-L1 inhibitor based on a tetrahydroisoquinoline scaffold, with a KD of 21.31 μM for binding to hPD-L1, and it blocks the PD-1/PD-L1 interaction. PD-1/PD-L1-IN-68 restores T cell immune function, thereby promoting the death of PD-L1+ cancer cells. PD-1/PD-L1-IN-68 can be used in studies related to liver cancer. | |||||||||||||||||||||
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