3056612-67-7
3056612-67-7
Chemical Structure
PROTAC USP7 Degrader-2
- CAS No.: 3056612-67-7
- Formula:C42H44Cl2N8O6S
- Molecular Weight:859.82
InChIKey: NSUMVMMLIUGUOY-UHFFFAOYSA-N
SMILES: CC1=C(C(C2=CC=NC3=C2SC(CN4C(C=CN(C4=O)CCCCCNC5=CC=CC6=C5C(N(C6=O)C7CCC(NC7=O)=O)=O)=O)=C3)=CC(Cl)=C1)NC8CCCNC8.Cl
Biological Activity: PROTAC USP7 Degrader-2 (Compound D16) is an efficient and selective USP7 PROTAC degrader with a DC50 of 1.91 μM (in TE-12 cells). PROTAC USP7 Degrader-2 inhibits the migration of upper gastrointestinal tract (UGI) cancer cells and shows relatively weak anti-proliferative activity. PROTAC USP7 Degrader-2 can be used in the research of metastatic upper gastrointestinal cancer.
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PROTAC USP7 Degrader-2 | PROTAC USP7 Degrader-2 (Compound D16) is an efficient and selective USP7 PROTAC degrader with a DC50 of 1.91 μM (in TE-12 cells). PROTAC USP7 Degrader-2 inhibits the migration of upper gastrointestinal tract (UGI) cancer cells and shows relatively weak anti-proliferative activity. PROTAC USP7 Degrader-2 can be used in the research of metastatic upper gastrointestinal cancer. | |||||||||||||||||||||
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