3057053-13-8
3057053-13-8
Chemical Structure
JAK2-IN-22
- CAS No.: 3057053-13-8
- Formula:C33H34FN7O5
- Molecular Weight:627.67
InChIKey: RKHCFTDWASPBEN-ZEQKJWHPSA-N
SMILES: O=C1N([C@H]2C[C@@H](CC2)NC(OC)=O)C3=CC(NC4=CC(C5=CC(C#N)=CC=C5)=CC(NC(C6(CCOCC6)F)=O)=C4)=NC=C3N1C
Biological Activity: JAK2-IN-22 is a bicyclic urea compound with potent binding inhibitory activity against wild-type and V617F mutant JH2 kinases (IC50 ≤ 10 nM). JAK2-IN-22 can be used in research related to various diseases including cancer[1].
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JAK2-IN-22 | JAK2-IN-22 is a bicyclic urea compound with potent binding inhibitory activity against wild-type and V617F mutant JH2 kinases (IC50 ≤ 10 nM). JAK2-IN-22 can be used in research related to various diseases including cancer. | |||||||||||||||||||||
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