3057206-40-0
3057206-40-0
Chemical Structure
PAR4 antagonist 3
- CAS No.: 3057206-40-0
- Formula:C22H16FN3O5S
- Molecular Weight:453.44
InChIKey: RBFSJRLVUDQWIG-UHFFFAOYSA-N
SMILES: FC1=CC=C(OCC2COC3=CC=C4C(OC(C5=CN6C(SC(OC)=N6)=N5)=C4)=C3O2)C=C1
Biological Activity: PAR4 antagonist 3 (Compound 36) is a selective antagonist for protease activated receptor 4 (PAR4). PAR4 antagonist 3 exhibits antiplatelet efficacy with IC50 of 26.1 nM. PAR4 antagonist 3 improves metabolic stablility in human liver microsomes with T1/2 of 97.6 min[1].
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PAR4 antagonist 3 | PAR4 antagonist 3 (Compound 36) is a selective antagonist for protease activated receptor 4 (PAR4). PAR4 antagonist 3 exhibits antiplatelet efficacy with IC50 of 26.1 nM. PAR4 antagonist 3 improves metabolic stablility in human liver microsomes with T1/2 of 97.6 min. | |||||||||||||||||||||
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