3057615-66-1
3057615-66-1
Chemical Structure
CHK1-IN-9
- CAS No.: 3057615-66-1
- Formula:C19H18F2N8O
- Molecular Weight:412.40
InChIKey: SIJZFZFUKHLAEE-NSHDSACASA-N
SMILES: N#CC1=NC=C(NC2=NC=C3C(C=CC(N3CC(F)F)=O)=N2)C=C1N[C@@H]4CNCC4
Biological Activity: CHK1-IN-9 (compound 11) is an orally active CHK1 inhibitor with an IC50 value of 0.55 nM. CHK1-IN-9 can enhance the effect of DNA-damaging drugs on tumor cells. CHK1-IN-9 has synergistic anticancer effects with Gemcitabine (HY-17026)[1].
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CHK1-IN-9 | CHK1-IN-9 (compound 11) is an orally active CHK1 inhibitor with an IC50 value of 0.55 nM. CHK1-IN-9 can enhance the effect of DNA-damaging drugs on tumor cells. CHK1-IN-9 has synergistic anticancer effects with Gemcitabine (HY-17026). | |||||||||||||||||||||
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