3059496-70-4
Chemical Structure
PF-07976016
Synonym(s): GIPR antagonist 4
- CAS No.: 3059496-70-4
- Formula:C28H29N3O4
- Molecular Weight:471.55
InChIKey: IGBNWQQJEYDUJS-RUZDIDTESA-N
SMILES: OC(C(C=C1)=CC=C1C(C=C2)=CC=C2NC([C@@H]3N(CCC3)C(NC4=CC=C(C(C)C)C=C4)=O)=O)=O
Biological Activity: PF-07976016 (GIPR antagonist 4) is an orally active GIPR antagonist with an IC50 of 4.1 nM. PF-07976016 (GIPR antagonist 4) exerts its antagonistic effect by competitively binding to GIPR and blocking the increase in Gαs-mediated cAMP production induced by GIP agonists. The combination of GIPR antagonist 4 and Liraglutide (HY-P0014) can enhance the weight loss effect of the single drug. PF-07976016 (GIPR antagonist 4) can be used for research related to obesity and metabolic diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-07976016 | 98.08% | PF-07976016 (GIPR antagonist 4) is an orally active GIPR antagonist with an IC50 of 4.1 nM. PF-07976016 (GIPR antagonist 4) exerts its antagonistic effect by competitively binding to GIPR and blocking the increase in Gαs-mediated cAMP production induced by GIP agonists. The combination of GIPR antagonist 4 and Liraglutide (HY-P0014) can enhance the weight loss effect of the single drug. PF-07976016 (GIPR antagonist 4) can be used for research related to obesity and metabolic diseases. | ||||||||||||||||||||
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