3059965-71-5
3059965-71-5
Chemical Structure
NLRP3-IN-62
- CAS No.: 3059965-71-5
- Formula:C21H15F3N4O3
- Molecular Weight:428.36
InChIKey: PWBIFRGGKGATQI-UHFFFAOYSA-N
SMILES: O=C1C=C2C(CN(C2)C3=NC4=NC(C5=C(C=C(C(F)(F)F)C=C5C)O)=CC=C4O3)=CN1
Biological Activity: NLRP3-IN-62 (Compound 1) is an inhibitor for NLRP3. NLRP3-IN-62 inhibits pyroptosis in THP-1 cell with an IC50 of 0.7 nM, inhibits IL-β release with an IC50 of 108.5 nM[1].
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NLRP3-IN-62 | NLRP3-IN-62 (Compound 1) is an inhibitor for NLRP3. NLRP3-IN-62 inhibits pyroptosis in THP-1 cell with an IC50 of 0.7 nM, inhibits IL-β release with an IC50 of 108.5 nM. | |||||||||||||||||||||
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