3060519-67-4
3060519-67-4
Chemical Structure
MS7829
- CAS No.: 3060519-67-4
- Formula:C44H57Cl2N9O6S
- Molecular Weight:910.95
InChIKey: IRYLYWHKMYJCPG-ZHACJKMWSA-N
SMILES: ClC1=C(NC2=C3CN(C(CO)=O)CC2)C3=C(C4=NN(CC(NCCCCCCCCCNC(CCC5=CC=C(N6C(CN(C(/C=C/CN(C)C)=O)CC6)=O)S5)=O)=O)C=C4)C=C1Cl
Biological Activity: MS7829 is a deubiquitinase-targeting chimera (DUBTAC) that targets cGAS. MS7829 recruits OTUB1 to cGAS, binds covalently to OTUB1, stabilizes the protein abundance of cGAS, and activates the cGAS-STING-IRF3 innate immune signaling pathway in an OTUB1-dependent manner. MS7829 is applicable to cancer-related research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
MS7829 | MS7829 is a deubiquitinase-targeting chimera (DUBTAC) that targets cGAS. MS7829 recruits OTUB1 to cGAS, binds covalently to OTUB1, stabilizes the protein abundance of cGAS, and activates the cGAS-STING-IRF3 innate immune signaling pathway in an OTUB1-dependent manner. MS7829 is applicable to cancer-related research. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
