3060520-82-0
3060520-82-0
Chemical Structure
MS5128
- CAS No.: 3060520-82-0
- Formula:C49H55F2N7O7S
- Molecular Weight:924.07
InChIKey: DHNGODQJUDRGTL-FMIVXFBMSA-N
SMILES: O=C(C1=CC=CC(C2=NC(NC(C3(CC3)C4=CC=C5OC(F)(OC5=C4)F)=O)=CC=C2C)=C1)NCCCCCCNC(CCC6=CC=C(S6)C(N7CC8CC(C7)N8C(/C=C/CN(C)C)=O)=O)=O
Biological Activity: MS5128 is an OTUB1-based deubiquitinase-targeting chimera (DUBTAC) targeting CFTR. MS5128 recruits OTUB1 to CFTR to induce deubiquitination and stabilization of CFTR. MS5128 can be used for the research of cystic fibrosis[1]. (Blue: CFTR Ligand (HY-183724); Pink: OTUB1 Ligand (HY-13262); Black: Linker)
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MS5128 | MS5128 is an OTUB1-based deubiquitinase-targeting chimera (DUBTAC) targeting CFTR. MS5128 recruits OTUB1 to CFTR to induce deubiquitination and stabilization of CFTR. MS5128 can be used for the research of cystic fibrosis. (Blue: CFTR Ligand (HY-183724); Pink: OTUB1 Ligand (HY-13262); Black: Linker) | |||||||||||||||||||||
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