3063333-21-8
Chemical Structure
8-epi-Meropenem
Synonym(s): JDB-1-200
- CAS No.: 3063333-21-8
- Formula:C17H25N3O5S
- Molecular Weight:383.46
InChIKey: DMJNNHOOLUXYBV-AYAQEJOPSA-N
SMILES: O=C(C(N12)=C(S[C@@H]3CN[C@H](C(N(C)C)=O)C3)[C@H](C)[C@]2([H])[C@@H]([C@@H](O)C)C1=O)O
Biological Activity: 8-epi-Meropenem (JDB-1-200) is a Meropenem (HY-13678) derivative with antibacterial activity. 8-epi-Meropenem is an inhibitor of KPC-2 (IC50 210 nM) and CTX-M-15 (IC50 215 nM). 8-epi-Meropenem also acts on bacterial PBPs to interfere with peptidoglycan synthesis. 8-epi-Meropenem has in vitro activity against KPC-producing Enterobacterales, exhibits strain-dependent activity against Acinetobacter baumannii, and has reduced activity against Pseudomonas aeruginosa. 8-epi-Meropenem can be used for research related to bacterial infections[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
8-epi-Meropenem | 8-epi-Meropenem (JDB-1-200) is a Meropenem (HY-13678) derivative with antibacterial activity. 8-epi-Meropenem is an inhibitor of KPC-2 (IC50 210 nM) and CTX-M-15 (IC50 215 nM). 8-epi-Meropenem also acts on bacterial PBPs to interfere with peptidoglycan synthesis. 8-epi-Meropenem has in vitro activity against KPC-producing Enterobacterales, exhibits strain-dependent activity against Acinetobacter baumannii, and has reduced activity against Pseudomonas aeruginosa. 8-epi-Meropenem can be used for research related to bacterial infections. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
