3067202-14-3
3067202-14-3
Chemical Structure
ChREBPα/14-3-3 regulator-1
- CAS No.: 3067202-14-3
- Formula:C16H15F3NO5P
- Molecular Weight:389.26
InChIKey: CWLSIOCFRIMBMV-UHFFFAOYSA-N
SMILES: FC1=CC=CC(C(F)(F)CNC(COC2=C(P(O)(O)=O)C=CC=C2)=O)=C1
Biological Activity: ChREBPα/14-3-3 regulator-1 is a molecular glue that selectively stabilizes ChREBPα/14-3-3 PPI, with an EC50 of 3.8 μM. ChREBPα/14-3-3 regulator-1 sequesters ChREBPα in the cytoplasm, inhibits ChREBPβ and TXNIP responses, reduces glucolipotoxicity-induced β-cell death, and maintains β-cell identity and function. ChREBPα/14-3-3 regulator-1 can be used in studies related to type 2 diabetes[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ChREBPα/14-3-3 regulator-1 | 98.36% | ChREBPα/14-3-3 regulator-1 is a molecular glue that selectively stabilizes ChREBPα/14-3-3 PPI, with an EC50 of 3.8 μM. ChREBPα/14-3-3 regulator-1 sequesters ChREBPα in the cytoplasm, inhibits ChREBPβ and TXNIP responses, reduces glucolipotoxicity-induced β-cell death, and maintains β-cell identity and function. ChREBPα/14-3-3 regulator-1 can be used in studies related to type 2 diabetes. | ||||||||||||||||||||
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