3069891-88-6
3069891-88-6
Chemical Structure
NEK7 degrader-4
- CAS No.: 3069891-88-6
- Formula:C20H19Cl2FN4O3
- Molecular Weight:453.29
IUPAC Name: N-(3,5-dichloro-4-(2,6-dioxopiperidin-3-yl)benzyl)-2-(5-fluoropyrimidin-2-yl)-2-methylpropanamide
InChIKey: LFSWKBNXONLSKK-UHFFFAOYSA-N
SMILES: O=C1NC(C(CC1)C2=C(C=C(CNC(C(C)(C)C3=NC=C(C=N3)F)=O)C=C2Cl)Cl)=O
Biological Activity: NEK7 degrader-4 is a NEK7 molecular glue degrader with a DC50 of 9 nM. NEK7 degrader-4 can be used for autoinflammatory and autoimmune disorders like multiple sclerosis, neurodegeneraive diseases like Alzheimer's disease and cardiovascular and melabolic disorders like pericarditis and Type 2 diabetes research[1].
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NEK7 degrader-4 | NEK7 degrader-4 is a NEK7 molecular glue degrader with a DC50 of 9 nM. NEK7 degrader-4 can be used for autoinflammatory and autoimmune disorders like multiple sclerosis, neurodegeneraive diseases like Alzheimer's disease and cardiovascular and melabolic disorders like pericarditis and Type 2 diabetes research. | |||||||||||||||||||||
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