3072761-08-8
Chemical Structure
Nrf2/HO-1 activator 4
- CAS No.: 3072761-08-8
- Formula:C27H27FN6O2S
- Molecular Weight:518.61
InChIKey: LCDRTZRDAWECIU-UHFFFAOYSA-N
SMILES: CC(C)COC1=CC=C(C2=NC(C)=C(C(NC(C)(C3=CN(C4=CC=C(F)C=C4)N=N3)C)=O)S2)C=C1C#N
Biological Activity: Nrf2/HO-1 activator 4 is a Nrf2/HO-1 activator. Nrf2/HO-1 activator 4 inhibits nitric oxide production and the expression of pro-inflammatory cytokines IL-1β, IL-6, TNF-α, as well as upstream inflammatory enzymes COX-2 and iNOS. Nrf2/HO-1 activator 4 reduces ROS accumulation, and restores GSH levels and SOD activity. Nrf2/HO-1 activator 4 ameliorates depression-like behaviors in mice. Nrf2/HO-1 activator 4 can be used for research on major depressive disorder[1].
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Nrf2/HO-1 activator 4 | Nrf2/HO-1 activator 4 is a Nrf2/HO-1 activator. Nrf2/HO-1 activator 4 inhibits nitric oxide production and the expression of pro-inflammatory cytokines IL-1β, IL-6, TNF-α, as well as upstream inflammatory enzymes COX-2 and iNOS. Nrf2/HO-1 activator 4 reduces ROS accumulation, and restores GSH levels and SOD activity. Nrf2/HO-1 activator 4 ameliorates depression-like behaviors in mice. Nrf2/HO-1 activator 4 can be used for research on major depressive disorder. | |||||||||||||||||||||
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