3075162-42-1
3075162-42-1
Chemical Structure
PKM2 agonist-1
- CAS No.: 3075162-42-1
- Formula:C24H23N5O4S2
- Molecular Weight:509.60
InChIKey: NMBABIRNQFJWIE-UHFFFAOYSA-N
SMILES: O=S(NC1=CC=C(C=C1)C2=NC=CN2C3CN(C3)S(=O)(C4CC4)=O)(C5=CC=CC6=CC=CN=C65)=O
Biological Activity: PKM2 agonist-1 (Compound D16) is a highly effective, allosteric PKM2 agonist with an AC50 value of 77 nM. PKM2 agonist-1 inhibits Ang II-induced smooth muscle cell phenotypic switching. PKM2 agonist-1 effectively prevents aortic dissection and results in reduced mortality[1].
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PKM2 agonist-1 | PKM2 agonist-1 (Compound D16) is a highly effective, allosteric PKM2 agonist with an AC50 value of 77 nM. PKM2 agonist-1 inhibits Ang II-induced smooth muscle cell phenotypic switching. PKM2 agonist-1 effectively prevents aortic dissection and results in reduced mortality. | |||||||||||||||||||||
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