3076770-93-6
3076770-93-6
Chemical Structure
GLP-1R agonist 29
- CAS No.: 3076770-93-6
- Formula:C49H48F2N10O5
- Molecular Weight:894.97
InChIKey: UAFHBRZGYKKCIE-QJZDMWAASA-N
SMILES: CC1=C(F)C(C)=CC(N2C(N3C=CN(C4=CC=C(N(C5CCC5)N=C6)C6=C4F)C3=O)=C7[C@H](C)N(C(C8=CC9=CC(C%10CCOCC%10)=CC=C9N8[C@@]%11(C%12=NOC(N%12)=O)C[C@@H]%11C)=O)CCC7=N2)=C1
Biological Activity: GLP-1R agonist 29 (Compound 20) is the agonist for GLP-1R that induces hGLP-1R mediated cAMP stimulation with an EC50 of 0.018 nM. GLP-1R agonist 29 exhibits good pharmacokinetics characteristics with good body exposure of AUC0-∞,sc of 77688 ng·h/mL[1].
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GLP-1R agonist 29 | GLP-1R agonist 29 (Compound 20) is the agonist for GLP-1R that induces hGLP-1R mediated cAMP stimulation with an EC50 of 0.018 nM. GLP-1R agonist 29 exhibits good pharmacokinetics characteristics with good body exposure of AUC0-∞,sc of 77688 ng·h/mL. | |||||||||||||||||||||
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