3080627-61-5
3080627-61-5
Chemical Structure
PDE4-IN-32
- CAS No.: 3080627-61-5
- Formula:C20H16O4
- Molecular Weight:320.34
InChIKey: AJIVZLFWSQQGDB-UHFFFAOYSA-N
SMILES: COC1=C2C(C=C(O2)C3CC3)=C(C=C1)C4=CC=C5C(OCC5=C4)=O
Biological Activity: PDE4-IN-32 (Compound B05) is a selective, blood-brain barrier permeable PDE4B and PDE4D inhibitor with IC50 values of 13.7 nM and 23.8 nM, respectively. PDE4-IN-32 promotes the recovery of motor and cognitive function in MCAO/R mouse models. PDE4-IN-32 reduces cerebral edema. PDE4-IN-32 can be used for the research of ischemic stroke[1].
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PDE4-IN-32 | PDE4-IN-32 (Compound B05) is a selective, blood-brain barrier permeable PDE4B and PDE4D inhibitor with IC50 values of 13.7 nM and 23.8 nM, respectively. PDE4-IN-32 promotes the recovery of motor and cognitive function in MCAO/R mouse models. PDE4-IN-32 reduces cerebral edema. PDE4-IN-32 can be used for the research of ischemic stroke. | |||||||||||||||||||||
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