3080812-16-1
3080812-16-1
Chemical Structure
CDC20-IN-2
- CAS No.: 3080812-16-1
- Formula:C21H15Cl4F6N7O3S
- Molecular Weight:701.26
InChIKey: RTJMCSRSLLFNFQ-UHFFFAOYSA-N
SMILES: FC(F)(F)C1=CC=C(NC2=CC(Cl)=NC(NC(NC(OCCNC(C3=CN=C(C(F)(F)F)S3)=O)=O)C(Cl)(Cl)Cl)=N2)C=C1
Biological Activity: CDC20-IN-2 (14c), a Cdc20 inhibitor (KD: 7.65 μM), causes G2/M phase arrest and promotes DNA damage accumulation. CDC20-IN-2 (14c) stabilizes key substrates such as Cyclin B1 and Bim, leading to enhanced apoptosis and suppression of tumor cell proliferation and migration[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CDC20-IN-2 | CDC20-IN-2 (14c), a Cdc20 inhibitor (KD: 7.65 μM), causes G2/M phase arrest and promotes DNA damage accumulation. CDC20-IN-2 (14c) stabilizes key substrates such as Cyclin B1 and Bim, leading to enhanced apoptosis and suppression of tumor cell proliferation and migration. | |||||||||||||||||||||
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