3082221-87-9
3082221-87-9
Chemical Structure
SphK2-IN-4
- CAS No.: 3082221-87-9
- Formula:C21H27F3N2O5S
- Molecular Weight:476.51
InChIKey: XLWPHFIVCDQGFL-TULZRXOXSA-N
SMILES: CCCCCOC1=CC=C(CC/C=C2SC(N(CCN)C\2=O)=O)C=C1.O=C(O)C(F)(F)F
Biological Activity: SphK2-IN-4 is a selective SphK2 inhibitor (IC50=6.2 μM) with extremely low activity against SphK1 (IC50 > 50 μM). SphK2-IN-4 exhibits broad-spectrum antiproliferative activity against colorectal cancer cells and induces apoptosis[1].
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SphK2-IN-4 | SphK2-IN-4 is a selective SphK2 inhibitor (IC50=6.2 μM) with extremely low activity against SphK1 (IC50 > 50 μM). SphK2-IN-4 exhibits broad-spectrum antiproliferative activity against colorectal cancer cells and induces apoptosis. | |||||||||||||||||||||
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