3084710-09-5
3084710-09-5
Chemical Structure
CRBN ligand-186
- CAS No.: 3084710-09-5
- Formula:C44H48F2N8O11S2
- Molecular Weight:967.03
InChIKey: ARMCIGXAGASBRH-QGFKTNLFSA-N
SMILES: N#CC(C(NS(=O)(N(CC)C)=O)=CC=C1F)=C1OC(C=C2C3=O)=CC=C2N=CN3[C@@H]4COC5(C4)CCN(CC5)C(CN6CCC(CC6)C7=CC=C(C=C7OS(=O)(F)=O)C8CCC(NC8=O)=O)=O
Biological Activity: CRBN ligand-186 (compound B1) is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit cereblon protein. CRBN ligand-891 can be used in the synthesis of PROTACs. CRBN ligand-186 can be used in cancer research[1].
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CRBN ligand-186 | CRBN ligand-186 (compound B1) is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit cereblon protein. CRBN ligand-891 can be used in the synthesis of PROTACs. CRBN ligand-186 can be used in cancer research. | |||||||||||||||||||||
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