3085716-86-2
Chemical Structure
IPR agonist-1
- CAS No.: 3085716-86-2
- Formula:C25H24D3N3O3
- Molecular Weight:420.52
InChIKey: SBEZNIGCIZCMID-RVOBKXSRSA-N
SMILES: [2H]C([2H])([2H])N([C@@H]1CC[C@H](OCC(O)=O)CC1)C2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N=C2
Biological Activity: IPR agonist-1 is a prostaglandin-based IP receptor agonist. IPR agonist-1 binds to the IP receptor, forms hydrogen bonds with Tyr75-Ser168-Arg279, and undergoes π-π stacking with Tyr281, thereby triggering downstream signaling pathways. IPR agonist-1 inhibits ADP (Adenosine 5'-diphosphate) (HY-W010918)-induced platelet aggregation in rabbit platelet-rich plasma. IPR agonist-1 can be used in the research of pulmonary arterial hypertension[1].
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IPR agonist-1 | IPR agonist-1 is a prostaglandin-based IP receptor agonist. IPR agonist-1 binds to the IP receptor, forms hydrogen bonds with Tyr75-Ser168-Arg279, and undergoes π-π stacking with Tyr281, thereby triggering downstream signaling pathways. IPR agonist-1 inhibits ADP (Adenosine 5'-diphosphate) (HY-W010918)-induced platelet aggregation in rabbit platelet-rich plasma. IPR agonist-1 can be used in the research of pulmonary arterial hypertension. | |||||||||||||||||||||
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