3086289-71-3
3086289-71-3
Chemical Structure
SHP2-IN-37
- CAS No.: 3086289-71-3
- Formula:C19H22Cl2N4O2S
- Molecular Weight:441.37
InChIKey: SNTOHKBZAXOGAV-KPZWWZAWSA-N
SMILES: ClC1=C(Cl)C(SC2=CN=C(N(CC3)CCC43[C@H](N)[C@H](C)OC4)C=[N+]2[O-])=CC=C1
Biological Activity: SHP2-IN-37 (compound C5) is a potent and selective SHP2 allosteric inhibitor with an IC50 of 0.023 μM. SHP2-IN-37 exhibits antiproliferative effect on KYSE-520 and MV-411 cells with IC50s of 6.97 and 0.67 μM, respectively[1]
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SHP2-IN-37 | 96.36% | SHP2-IN-37 (compound C5) is a potent and selective SHP2 allosteric inhibitor with an IC50 of 0.023 μM. SHP2-IN-37 exhibits antiproliferative effect on KYSE-520 and MV-411 cells with IC50s of 6.97 and 0.67 μM, respectively | ||||||||||||||||||||
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