3092446-09-5
3092446-09-5
Chemical Structure
SOS1-IN-25
- CAS No.: 3092446-09-5
- Formula:C29H37N5O2S
- Molecular Weight:519.70
InChIKey: SHNVBWFKFABUAM-GOSISDBHSA-N
SMILES: CC1=NC(N[C@@H](C2=CC(C3=CC=CC=C3CNC)=CS2)C)=C4C(C(C)(C)C(N(C5CCOCC5)C4)=O)=N1
Biological Activity: SOS1-IN-25 is an SOS1 inhibitor. SOS1-IN-25 exhibits inhibitory activity against KRASG12C/SOS1 complex formation (IC50 = 11.11 nM). SOS1-IN-25 leads to a dose-dependent decrease in pERK levels. SOS1-IN-25 can be used for the study of leukemia[1].
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SOS1-IN-25 | SOS1-IN-25 is an SOS1 inhibitor. SOS1-IN-25 exhibits inhibitory activity against KRASG12C/SOS1 complex formation (IC50 = 11.11 nM). SOS1-IN-25 leads to a dose-dependent decrease in pERK levels. SOS1-IN-25 can be used for the study of leukemia. | |||||||||||||||||||||
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