3093642-21-5
3093642-21-5
Chemical Structure
PROTAC EZH2 Degrader-14
- CAS No.: 3093642-21-5
- Formula:C58H71N11O11
- Molecular Weight:1098.25
InChIKey: TYCNOBOSAAHGPM-UHFFFAOYSA-N
SMILES: CCN(C1=CC(C2=CC=C(CN3CCN(C(C4=CN(N=N4)CCOCCOCCOCCNC5=C6C(C(N(C6=O)C7CCC(NC7=O)=O)=O)=CC=C5)=O)CC3)C=C2)=CC(C(NCC8=C(C)C=C(C)NC8=O)=O)=C1C)C9CCOCC9
Biological Activity: PROTAC EZH2 Degrader-14 is an EZH2 PROTAC degrader, with an IC50 of 18.21 μM against diffuse large B-cell lymphoma cells, and exhibits no antiproliferative activity against non-target cells at concentrations up to 30.00 μM. PROTAC EZH2 Degrader-14 can be used in studies related to diffuse large B-cell lymphoma[1].
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PROTAC EZH2 Degrader-14 | PROTAC EZH2 Degrader-14 is an EZH2 PROTAC degrader, with an IC50 of 18.21 μM against diffuse large B-cell lymphoma cells, and exhibits no antiproliferative activity against non-target cells at concentrations up to 30.00 μM. PROTAC EZH2 Degrader-14 can be used in studies related to diffuse large B-cell lymphoma. | |||||||||||||||||||||
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