3093642-23-7
3093642-23-7
Chemical Structure
PROTAC EZH2 Degrader-17
- CAS No.: 3093642-23-7
- Formula:C62H79N11O13
- Molecular Weight:1186.36
InChIKey: NJLPIDDZLVCWBE-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2=CC=C(CN3CCN(CC3)C(C4=CN(CCOCCOCCOCCOCCOCCNC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)N=N4)=O)C=C2)=CC(N(C8CCOCC8)CC)=C1C)NCC9=C(C)C=C(C)NC9=O
Biological Activity: PROTAC EZH2 Degrader-17 (compound 52) is a PROTAC protein degrader targeting EZH2 with an antiproliferative IC50 of 18.32 μM in lymphoma cells. PROTAC EZH2 Degrader-17 exhibits antiproliferative activity against lymphoma cells. PROTAC EZH2 Degrader-17 can be used for the research of lymphoma[1].
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PROTAC EZH2 Degrader-17 | PROTAC EZH2 Degrader-17 (compound 52) is a PROTAC protein degrader targeting EZH2 with an antiproliferative IC50 of 18.32 μM in lymphoma cells. PROTAC EZH2 Degrader-17 exhibits antiproliferative activity against lymphoma cells. PROTAC EZH2 Degrader-17 can be used for the research of lymphoma. | |||||||||||||||||||||
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