3093724-62-7
3093724-62-7
Chemical Structure
HPK1-IN-58
- CAS No.: 3093724-62-7
- Formula:C26H30N8O
- Molecular Weight:470.57
InChIKey: DOQRDMNKFZAURQ-UHFFFAOYSA-N
SMILES: CNCC1=NC(N2C(C)(C)CCC2)=CC3=C1CN(C4=NC(C5=NN=C6N5C(C7)C7C6)=CC=C4)C3=O
Biological Activity: HPK1-IN-58 (Compound 26) is an inhibitor of HPK1 (IC50: 2.6 nM) and SLP76 (IC50: 20 nM). HPK1-IN-58 enhances IL-2 secretion and reverses PGE2-induced immunosuppression. HPK1-IN-58 can be used in anti-tumor immunity research[1].
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HPK1-IN-58 | HPK1-IN-58 (Compound 26) is an inhibitor of HPK1 (IC50: 2.6 nM) and SLP76 (IC50: 20 nM). HPK1-IN-58 enhances IL-2 secretion and reverses PGE2-induced immunosuppression. HPK1-IN-58 can be used in anti-tumor immunity research. | |||||||||||||||||||||
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