3093737-33-5
3093737-33-5
Chemical Structure
PROTAC BRD4 Degrader-50
- CAS No.: 3093737-33-5
- Formula:C39H41ClN8O4S
- Molecular Weight:753.31
InChIKey: DQGNINFYAAEZKL-FSRLHOSWSA-N
SMILES: O=C(NC1=O)CCC1N2CC3=CC(C4CCN(CCNC(C[C@@H](C5=NN=C(C)N56)N=C(C7=CC=C(Cl)C=C7)C8=C6SC(C)=C8C)=O)CC4)=CC=C3C2=O
Biological Activity: PROTAC BRD4 Degrader-50 is a BRD4 PROTAC degrader with a DC50 of 11.4 nM (HEK293). PROTAC BRD4 Degrader-50 induces BRD4 degradation via the proteasome and CRBN. PROTAC BRD4 Degrader-50 is applicable to cancer research[1].
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PROTAC BRD4 Degrader-50 | PROTAC BRD4 Degrader-50 is a BRD4 PROTAC degrader with a DC50 of 11.4 nM (HEK293). PROTAC BRD4 Degrader-50 induces BRD4 degradation via the proteasome and CRBN. PROTAC BRD4 Degrader-50 is applicable to cancer research. | |||||||||||||||||||||
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