3095344-37-6
3095344-37-6
Chemical Structure
PD-1/PD-L1-IN-60
- CAS No.: 3095344-37-6
- Formula:C53H70ClFN4O15
- Molecular Weight:1057.59
InChIKey: DDXREPRRFXCLKL-UHFFFAOYSA-N
SMILES: OCC(CO)(CO)N(CC1=CN(CCOCCOCCOCCOCCOCCOCCOCCF)N=N1)CC(C(OCC2=CC(O)=CC=C2)=C3)=CC(Cl)=C3OCC4=C(C)C(C5=CC6=C(OCCO6)C=C5)=CC=C4
Biological Activity: PD-1/PD-L1-IN-60 is the counterpart of the small-molecule immuno-probe [18F] LG‑8, and the two together enable integrated immuno-diagnosis and therapy. PD-1/PD-L1-IN-60 exhibits potent anti-tumor activity in mouse models of melanoma and lung cancer with high PD‑L1 uptake. PD-1/PD-L1-IN-60 can be used for relevant research on melanoma and lung cancer[1].
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PD-1/PD-L1-IN-60 | PD-1/PD-L1-IN-60 is the counterpart of the small-molecule immuno-probe [18F] LG‑8, and the two together enable integrated immuno-diagnosis and therapy. PD-1/PD-L1-IN-60 exhibits potent anti-tumor activity in mouse models of melanoma and lung cancer with high PD‑L1 uptake. PD-1/PD-L1-IN-60 can be used for relevant research on melanoma and lung cancer. | |||||||||||||||||||||
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