3096845-40-5
3096845-40-5
Chemical Structure
MPXV p37 protein-IN-1
- CAS No.: 3096845-40-5
- Formula:C18H15F2N3O2S
- Molecular Weight:375.39
InChIKey: UVQJEPQGJMULDU-BAUHJFHZSA-N
SMILES: [H][C@@]12[C@@]3([H])C[C@@]3([H])[C@@]([C@](C(N4NC(NC5=CC(F)=C(F)C=C5)=S)=O)([H])[C@@]2([H])C4=O)([H])C=C1
Biological Activity: MPXV p37 protein-IN-1 is a potent and orally active inhibitor of monkeypox virus (MPXV) p37 protein. MPXV p37 protein-IN-1 exhibits potent antivial activity against MPXV with an EC50 of 12.14 nM, with low cytotoxicity (CC50 = 304.63 μM). MPXV p37 protein-IN-1 demonstrates low toxicity and good tolerability in mice. MPXV p37 protein-IN-1 can be used for the research of anti-MPXV[1].
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MPXV p37 protein-IN-1 | MPXV p37 protein-IN-1 is a potent and orally active inhibitor of monkeypox virus (MPXV) p37 protein. MPXV p37 protein-IN-1 exhibits potent antivial activity against MPXV with an EC50 of 12.14 nM, with low cytotoxicity (CC50 = 304.63 μM). MPXV p37 protein-IN-1 demonstrates low toxicity and good tolerability in mice. MPXV p37 protein-IN-1 can be used for the research of anti-MPXV. | |||||||||||||||||||||
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