3103594-37-9
Chemical Structure
Pan-RAS-IN-8
- CAS No.: 3103594-37-9
- Formula:C51H63N9O7S
- Molecular Weight:946.17
InChIKey: GUBSFUQWACWQKP-LJJIEJLRSA-N
SMILES: O=C([C@H](CC1=NC2=CS1)NC([C@H]3[C@H](C)[C@@H]3C)=O)N4N[C@H](C(OCC(C)(C)CC5=[C@@]([C@@]6=C([C@H](C)OC)N=CC(C7=NN=C(C8CCN(C9COC9)CC8)O7)=C6)N(CC)C%10=C5C=C2C=C%10)=O)C%11CC4C%11
Biological Activity: Pan-RAS-IN-8 (Page 152, third row, third from left to right) is a pan-RAS inhibitor. Pan-RAS-IN-8 blocks the binding of RAS to downstream effector molecules by forming a ternary complex, thereby inhibiting the activation of the MAPK and PI3K-AKT signaling pathways. Pan-RAS-IN-8 can be used for the research of cancer, inflammatory diseases and autoimmune diseases[1].
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Pan-RAS-IN-8 | Pan-RAS-IN-8 (Page 152, third row, third from left to right) is a pan-RAS inhibitor. Pan-RAS-IN-8 blocks the binding of RAS to downstream effector molecules by forming a ternary complex, thereby inhibiting the activation of the MAPK and PI3K-AKT signaling pathways. Pan-RAS-IN-8 can be used for the research of cancer, inflammatory diseases and autoimmune diseases. | |||||||||||||||||||||
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