3104023-25-5
3104023-25-5
Chemical Structure
IL-4-IN-3
- CAS No.: 3104023-25-5
- Formula:C18H13N3O2
- Molecular Weight:303.31
InChIKey: OYNDNZZKZGGOKL-UHFFFAOYSA-N
SMILES: N#CC1=C(N)N=C(C2=CC=CC=C2)C=C1C3=CC(O)=C(O)C=C3
Biological Activity: IL-4-IN-3 (Compound 15/analog 15) is a selective, reversible small-molecule IL-4 inhibitor with a Kd of 31.9 nM for IL-4. IL-4-IN-3 inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes and Ramos B lymphocytes. IL-4-IN-3 can be used in research related to allergic inflammation, cancer, autoimmune diseases, asthma and arthritis[1].
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IL-4-IN-3 | IL-4-IN-3 (Compound 15/analog 15) is a selective, reversible small-molecule IL-4 inhibitor with a Kd of 31.9 nM for IL-4. IL-4-IN-3 inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes and Ramos B lymphocytes. IL-4-IN-3 can be used in research related to allergic inflammation, cancer, autoimmune diseases, asthma and arthritis. | |||||||||||||||||||||
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