3104610-92-3
3104610-92-3
Chemical Structure
HDAC3-IN-7
- CAS No.: 3104610-92-3
- Formula:C25H37N5O4S
- Molecular Weight:503.66
InChIKey: LWUHHMSKYVQLQF-UHFFFAOYSA-N
SMILES: O=C(NNCCC)CCCCCCNC(C1=CN=C(C2=CC=C(NC(OC(C)(C)C)=O)C=C2)S1)=O
Biological Activity: HDAC3-IN-7 (Compound 8ae) is a selective HDAC3 inhibitor with an IC50 value of 311 nM. HDAC3-IN-7 degrades PD-L1 through the lysosome pathway mediated by Cathepsin B, exerting activities such as inhibiting tumor cell proliferation, migration, and invasion. HDAC3-IN-7 is promising for research of cancers[1].
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HDAC3-IN-7 | HDAC3-IN-7 (Compound 8ae) is a selective HDAC3 inhibitor with an IC50 value of 311 nM. HDAC3-IN-7 degrades PD-L1 through the lysosome pathway mediated by Cathepsin B, exerting activities such as inhibiting tumor cell proliferation, migration, and invasion. HDAC3-IN-7 is promising for research of cancers. | |||||||||||||||||||||
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