3105265-09-3
3105265-09-3
Chemical Structure
Hsp90β-IN-2
- CAS No.: 3105265-09-3
- Formula:C28H36N4O3
- Molecular Weight:476.61
InChIKey: YFVHMTJDFBXSBR-UHFFFAOYSA-N
SMILES: CCCC1=CC2=C(C(N3CCC(CC3)O)=CC(N4N=C(C5=C4CC(C)(CC5=O)C)CC)=C2)C(N1)=O
Biological Activity: Hsp90β-IN-2 (Compound 16B) is a selective Hsp90β inhibitor with KDs of 225 nM and 73.32 μM against Hsp90β and Hsp90α. KUNB106 exhibits antiproliferative activity against MDA-MB-231 cells, A549 and SKOV-3 cells. KUNB106 can be used for the study of triple negative breast cancer[1].
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Hsp90β-IN-2 | Hsp90β-IN-2 (Compound 16B) is a selective Hsp90β inhibitor with KDs of 225 nM and 73.32 μM against Hsp90β and Hsp90α. KUNB106 exhibits antiproliferative activity against MDA-MB-231 cells, A549 and SKOV-3 cells. KUNB106 can be used for the study of triple negative breast cancer. | |||||||||||||||||||||
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