3106089-54-4
Chemical Structure
Dehydroxy-oridonin-vinyl ester
- CAS No.: 3106089-54-4
- Formula:C23H26O5
- Molecular Weight:382.45
InChIKey: XATCGQQICKFBJX-SRLAHJPRSA-N
SMILES: O=C1[C@H]2[C@]3([H])C(C)(C)CC=C[C@@]3(CO2)[C@@]4([H])[C@]1(C5=O)[C@@H](OC(C=C)=O)[C@H](C5=C)CC4
Biological Activity: Dehydroxy-oridonin-vinyl ester (Compound 6k) is an anti-cancer agent. Dehydroxy-oridonin-vinyl ester exhibits extremely strong anti-proliferative activity against SU-DHL-6 cells, with its IC₅₀ value being 0.12 μM. Dehydroxy-oridonin-vinyl ester induces cell apoptosis by inhibiting the activation of the PI3K/Akt signaling pathway, without affecting the cell cycle progression. Dehydroxy-oridonin-vinyl can be used for the study of lymphoma[1].
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Dehydroxy-oridonin-vinyl ester | Dehydroxy-oridonin-vinyl ester (Compound 6k) is an anti-cancer agent. Dehydroxy-oridonin-vinyl ester exhibits extremely strong anti-proliferative activity against SU-DHL-6 cells, with its IC₅₀ value being 0.12 μM. Dehydroxy-oridonin-vinyl ester induces cell apoptosis by inhibiting the activation of the PI3K/Akt signaling pathway, without affecting the cell cycle progression. Dehydroxy-oridonin-vinyl can be used for the study of lymphoma. | |||||||||||||||||||||
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