3106140-37-5
3106140-37-5
Chemical Structure
LEX-K02
- CAS No.: 3106140-37-5
- Formula:C28H22F4N2O3S
- Molecular Weight:542.54
InChIKey: KNQXZJQYWHOJLF-HOTGVXAUSA-N
SMILES: O=C(C1=CSC(C2=CC(F)=C(C=C2)F)=N1)N[C@@H](C)C(O[C@@H](C)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)=O
Biological Activity: LEX-K02 is a broad-spectrum and potent thiazole amide antifungal agent with an EC50 of 0.140 μM. LEX-K02 inhibits fungal growth by disrupting the fungal cell membrane to cause leakage of intracellular substances and targeting the map00510 pathway to interfere with N-glycan biosynthesis. LEX-K02 can be used in studies related to Gaeumannomyces graminis infection[1].
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LEX-K02 | LEX-K02 is a broad-spectrum and potent thiazole amide antifungal agent with an EC50 of 0.140 μM. LEX-K02 inhibits fungal growth by disrupting the fungal cell membrane to cause leakage of intracellular substances and targeting the map00510 pathway to interfere with N-glycan biosynthesis. LEX-K02 can be used in studies related to Gaeumannomyces graminis infection. | |||||||||||||||||||||
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