3107904-59-3

XAT-14 Chemical Structure
3107904-59-3

Chemical Structure

XAT-14

  • CAS No.: 3107904-59-3
  • Formula:C21H18O5
  • Molecular Weight:350.36

InChIKey: WKCPNPKVMRFMAL-UHFFFAOYSA-N

SMILES: O=C1OC2=C(OCCCOCC3=CC=CC=C3)C4=C(C=CO4)C=C2C=C1

Biological Activity: XAT-14 is a Furanocoumarin derivative. XAT-14 competes with agonists to bind to the active pocket of MRGPRX2, inhibiting calcium influx and mast cell degranulation. XAT-14 suppresses the release of histamine, IL-8 and MCP-1 induced by Compound 48/80 (HY-115768). XAT-14 inhibits local allergic inflammation. XAT-14 can be used for the research of pseudo-allergic diseases[1].

Cat. No. Product Name Purity Description Pricing
HY-184281
XAT-14 98.50% XAT-14 is a Furanocoumarin derivative. XAT-14 competes with agonists to bind to the active pocket of MRGPRX2, inhibiting calcium influx and mast cell degranulation. XAT-14 suppresses the release of histamine, IL-8 and MCP-1 induced by Compound 48/80 (HY-115768). XAT-14 inhibits local allergic inflammation. XAT-14 can be used for the research of pseudo-allergic diseases.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References