3110518-96-9
3110518-96-9
Chemical Structure
15-LOX-1 inhibitor 2
- CAS No.: 3110518-96-9
- Formula:C22H27ClN2
- Molecular Weight:354.92
InChIKey: NTXITOPQAGVYKU-UHFFFAOYSA-N
SMILES: CCCCCCCNCC1=C(C2=CC=CC=C2)NC3=CC(Cl)=CC=C31
Biological Activity: 15-LOX-1 inhibitor 2 (Compound 5i) is an inhibitor of 15-lipoxygenase-1 (15-LOX-1) with an IC50 of 1.7 μM. 15-LOX-1 inhibitor 2 inhibits the activity of 15-LOX-1 enzyme, reduces the production of lipid peroxides, thereby inhibiting lipid peroxidation and protecting cells from cell death induced by RSL3 (HY-100218A). 15-LOX-1 inhibitor 2 can be used in research on cell death mechanisms, oxidative stress-related diseases and other fields[1].
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15-LOX-1 inhibitor 2 | 15-LOX-1 inhibitor 2 (Compound 5i) is an inhibitor of 15-lipoxygenase-1 (15-LOX-1) with an IC50 of 1.7 μM. 15-LOX-1 inhibitor 2 inhibits the activity of 15-LOX-1 enzyme, reduces the production of lipid peroxides, thereby inhibiting lipid peroxidation and protecting cells from cell death induced by RSL3 (HY-100218A). 15-LOX-1 inhibitor 2 can be used in research on cell death mechanisms, oxidative stress-related diseases and other fields. | |||||||||||||||||||||
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